A member of the public called emergency services after a man was spotted entering the River Mersey on Thursday.
Police arrived on scene near Garston Docks 4pm and brought the man ashore, services performed CPR but he was pronounced dead a short time later.
Investigations are underway to identify the man and the incident is not being treated as suspicious.
Wirral Coastguard,Liverpool and Crosby Coastguard, Marine Fire One, Northwest Ambulance Service, Merseyside Fire & Rescue were also in attendance.
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